dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Base Information

Chemical Name:dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate
CAS No.:336625-17-3
Molecular Formula:C₁₂H₁₃F₃IO₅P
Molecular Weight:452.106
Hs Code.:

Synonyms:dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Suppliers and Price of dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Chemical Property:

Purity/Quality:: 98% HPLC ^*data from raw suppliers

Safty Information:

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Technology Process of dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

There total 3 articles about dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 336625-15-1
ethyl (2-iodo-5-trifluoromethyl-phenoxy)acetate

: 756-79-6
dimethyl methane phosphonate

: 336625-17-3
dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Guidance literature:: dimethyl methane phosphonate; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

ethyl (2-iodo-5-trifluoromethyl-phenoxy)acetate; In tetrahydrofuran; hexane; for 2h;
DOI:10.1002/jlcr.441

Reference yield:

: 98-17-9
3-Trifluoromethylphenol

: 336625-17-3
dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / toluene; various solvent(s) / 0.08 h

1.2: 86 percent / iodine / toluene; various solvent(s) / 16 h / 20 °C

2.1: 48 percent / potassium carbonate / acetone / 16 h / Heating

3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.2: 22 percent / tetrahydrofuran; hexane / 2 h

With n-butyllithium; sodium hydride; potassium carbonate; In tetrahydrofuran; hexane; acetone; toluene;
DOI:10.1002/jlcr.441

Reference yield:

: 102771-00-6
2-iodo-5-(trifluoromethyl)phenol

: 336625-17-3
dimethyl [3-(2-iodo-5-trifluoromethyl-phenoxy)-2-oxo-propyl]-phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 48 percent / potassium carbonate / acetone / 16 h / Heating

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 22 percent / tetrahydrofuran; hexane / 2 h

With n-butyllithium; potassium carbonate; In tetrahydrofuran; hexane; acetone;
DOI:10.1002/jlcr.441