(S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Base Information

Chemical Name:(S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide
CAS No.:872516-20-6
Molecular Formula:C₂₃H₂₉NO₅
Molecular Weight:399.487
Hs Code.:

Synonyms:(S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Suppliers and Price of (S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

There total 6 articles about (S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 872516-12-6
(S)-(-)-1-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]pyrrolidine-2,5-dione

: 917-54-4
methyllithium

: 872516-20-6
(S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Guidance literature:: In pentane; at -78 ℃; for 6h;
DOI:10.1021/jo051584w

Reference yield:

: 872516-08-0
(S)-(-)-1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethylamine

: 872516-20-6
(S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether / 16 h / Heating

2: 280 mg / NaOAc; Ac₂O / 1 h / 85 °C

3: 66 percent / pentane / 6 h / -78 °C

With sodium acetate; acetic anhydride; In diethyl ether; pentane;
DOI:10.1021/jo051584w

Reference yield:

: 872516-04-6
(S)-(-)-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]carbamic acid tert-butyl ester

: 872516-20-6
(S)-(-)-N-[1-(benzyloxymethyl)-2-(3,4-dimethoxyphenyl)ethyl]-4-oxopentanamide

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / CF₃CO₂H / CH₂Cl₂ / 1 h / 20 °C

2: diethyl ether / 16 h / Heating

3: 280 mg / NaOAc; Ac₂O / 1 h / 85 °C

4: 66 percent / pentane / 6 h / -78 °C

With sodium acetate; acetic anhydride; trifluoroacetic acid; In diethyl ether; dichloromethane; pentane;
DOI:10.1021/jo051584w