(7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone

Base Information

Chemical Name:(7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone
CAS No.:164526-10-7
Molecular Formula:C₁₅H₁₁NO₅
Molecular Weight:285.256
Hs Code.:
DSSTox Substance ID:DTXSID801319820
ChEMBL ID:CHEMBL1483042
Mol file:164526-10-7.mol

Synonyms:164526-10-7;(7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone;(7-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(phenyl)methanone;(6-nitro-2,3-dihydro-1,4-benzodioxin-7-yl)-phenylmethanone;Oprea1_802540;Oprea1_827973;MLS000712416;CHEMBL1483042;DTXSID801319820;HMS2689E11;STK065488;AKOS001484977;SMR000282183;CS-0336937;SR-01000404100;SR-01000404100-1;6-BENZOYL-7-NITRO-2,3-DIHYDRO-1,4-BENZODIOXINE;(7-nitro-2,3-dihydro-1,4-benzodioxin-6-yl)(phenyl)methanone

Suppliers and Price of (7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(7-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(phenyl)methanone 97%
1g
$ 617.00

American Custom Chemicals Corporation
(7-NITRO-2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-PHENYL-METHANONE 95.00%
5MG
$ 502.44

Total 2 raw suppliers

Chemical Property of (7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:285.06372245
Heavy Atom Count:21
Complexity:401

Purity/Quality:

99% ^*data from raw suppliers

(7-Nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(phenyl)methanone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COC2=C(O1)C=C(C(=C2)[N+](=O)[O-])C(=O)C3=CC=CC=C3

Technology Process of (7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone

There total 3 articles about (7-Nitro-2,3-dihydro-benzo[1,4]dioxin-6-yl)-phenyl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 93637-87-7
2,3-dihydro-1,4-benzodioxin-6-yl(phenyl)methanone

: 164526-10-7
(7-nitro-2,3-dihydro-1,4-benzodioxin-6-yl)-(phenyl)methanone

Guidance literature:: With sulfuric acid; nitric acid; In acetic acid; at 10 - 20 ℃; for 1h;
DOI:10.1007/BF01169826

Reference yield:

: 493-09-4
benzo-1,4-dioxane

: 164526-10-7
(7-nitro-2,3-dihydro-1,4-benzodioxin-6-yl)-(phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: AlCl₃ / benzene / 2.5 h / 55 - 60 °C

2: 78 percent / HNO₃; AcOH / 0.5 h / 0 - 20 °C

With aluminium trichloride; nitric acid; acetic acid; In benzene; 1: Friedel-Crafts reaction;
DOI:10.1016/j.tet.2006.10.056

Reference yield:

: 98-88-4
benzoyl chloride

: 164526-10-7
(7-nitro-2,3-dihydro-1,4-benzodioxin-6-yl)-(phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: AlCl₃ / benzene / 2.5 h / 55 - 60 °C

2: 78 percent / HNO₃; AcOH / 0.5 h / 0 - 20 °C

With aluminium trichloride; nitric acid; acetic acid; In benzene; 1: Friedel-Crafts reaction;
DOI:10.1016/j.tet.2006.10.056