1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

Base Information

Chemical Name:1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester
CAS No.:1009816-09-4
Molecular Formula:C₂₄H₂₀FN₃O₅
Molecular Weight:449.438
Hs Code.:

Synonyms:1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

Suppliers and Price of 1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

There total 2 articles about 1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 757251-54-0
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxyamide

: C₁₂H₁₁ClO₃

: 1009816-09-4
1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

Guidance literature:: With 4-methyl-morpholine; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; at -20 - -10 ℃; for 1h;

Reference yield:

: 757251-54-0
4-(4-amino-3-fluorophenoxy)pyridine-2-carboxyamide

: 870647-41-9
1-(benzyloxycarbonyl)cyclopropanecarboxylic acid

: 1009816-09-4
1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

Guidance literature:: With 4-methyl-morpholine; thionyl chloride; In tetrahydrofuran; at 0 - 25.2 ℃; for 5.48333h; Product distribution / selectivity;

Reference yield:

: 1009816-09-4
1-[4-(2-carbamoylpyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

: 1009816-11-8
1-[4-(2-aminopyridin-4-yloxy)-2-fluorophenylcarbamoyl]cyclopropanecarboxylic acid benzyl ester

Guidance literature:: With [bis(acetoxy)iodo]benzene; In water; N,N-dimethyl-formamide; at 20 ℃; for 2.5h; Product distribution / selectivity;