6-Chloro-N-methylpyrazin-2-amine

Base Information

Chemical Name:6-Chloro-N-methylpyrazin-2-amine
CAS No.:848366-38-1
Molecular Formula:C5H6ClN3
Molecular Weight:143.576
Hs Code.:2933990090
Mol file:848366-38-1.mol

Synonyms:Pyrazinamine,6-chloro-N-methyl- (9CI);6-Chloro-N-methylpyrazin-2-amine;6-Chloro-N-methyl-pyrazin-2-amine;2-Chloro-6-(methylamino)pyrazine;

Suppliers and Price of 6-Chloro-N-methylpyrazin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-6-methylaminopyrazine
250mg
$ 55.00

SynQuest Laboratories
2-Chloro-6-(methylamino)pyrazine
500 mg
$ 16.00

Matrix Scientific
6-Chloro-N-methyl-2-pyrazinamine
2.500g
$ 720.00

Matrix Scientific
6-Chloro-N-methyl-2-pyrazinamine
500mg
$ 237.00

Crysdot
6-Chloro-N-methylpyrazin-2-amine 97%
25g
$ 155.00

Crysdot
6-Chloro-N-methylpyrazin-2-amine 97%
5g
$ 58.00

Crysdot
6-Chloro-N-methylpyrazin-2-amine 97%
10g
$ 86.00

Chemenu
6-Chloro-N-methyl-2-pyrazinamine 95%+
10g
$ 167.00

Chemenu
6-Chloro-N-methyl-2-pyrazinamine 95%+
5g
$ 91.00

Chemenu
6-Chloro-N-methyl-2-pyrazinamine 95%+
25g
$ 373.00

Total 33 raw suppliers

Chemical Property of 6-Chloro-N-methylpyrazin-2-amine

Chemical Property:

Vapor Pressure:0.0218mmHg at 25°C
Refractive Index:1.604
Boiling Point:250.4 °C at 760 mmHg
PKA:1.07±0.25(Predicted)
Flash Point:105.2 °C
PSA：37.81000
Density:1.338 g/cm³
LogP:1.24470
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-6-methylaminopyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 43
Safety Statements: 36/37

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Chloro-6-methylaminopyrazine

Technology Process of 6-Chloro-N-methylpyrazin-2-amine

There total 2 articles about 6-Chloro-N-methylpyrazin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 4774-14-5
2,6-dichloropyrazine

: 74-89-5
methylamine

: 848366-38-1
6-chloro-N-methylpyrazin-2-amine

Guidance literature:: In ethanol; at 80 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.tet.2018.08.040

Reference yield:

: 848366-38-1
6-chloro-N-methylpyrazin-2-amine

Guidance literature:: 2,4-Dichlorpyrimidin, Methylamin;

Reference yield: 98.3%

: tert-butyl (3R)-3-{(3-chloropyridin-2-yl)[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]amino}piperidine-1-carboxylate

: 848366-38-1
6-chloro-N-methylpyrazin-2-amine

: C₂₇H₃₁ClN₆O₃

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; In 1,4-dioxane; water; at 100 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.8b00650