N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

Base Information

Chemical Name:N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine
CAS No.:148854-73-3
Molecular Formula:C₂₇H₃₂ClN₇O₁₀S
Molecular Weight:682.111
Hs Code.:

Synonyms:N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

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Chemical Property of N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

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Technology Process of N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

There total 3 articles about N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 52450-18-7
3'-amino-3'-deoxythymidine

: 148854-64-2
4-Chloro-N-[1-{[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl]-amino}-1-methylsulfanyl-meth-(Z)-ylidene]-benzenesulfonamide

: 148854-73-3
N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

Guidance literature:: With silver nitrate; In triethylamine; N,N-dimethyl-formamide; for 18h; Ambient temperature;

Reference yield:

: 13068-12-7
N--4-chlorobenzenesulfonamide

: 148854-73-3
N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 18 h / 80 °C

2: 82 percent / AgNO₃ / dimethylformamide; triethylamine / 18 h / Ambient temperature

With silver nitrate; In pyridine; triethylamine; N,N-dimethyl-formamide;

Reference yield:

: 25152-20-9
5'-amino-5'-deoxythymidine

: 148854-73-3
N'-(p-chlorophenylsulfonyl)-N-(3'-deoxythymidin-3'-yl)-N''-(5'-deoxythymidin-5'-yl)guanidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 18 h / 80 °C

2: 82 percent / AgNO₃ / dimethylformamide; triethylamine / 18 h / Ambient temperature

With silver nitrate; In pyridine; triethylamine; N,N-dimethyl-formamide;