4-(3-(Trifluoromethyl)pyridin-2-YL)benzoic acid

Base Information

Chemical Name:4-(3-(Trifluoromethyl)pyridin-2-YL)benzoic acid
CAS No.:847446-88-2
Molecular Formula:C13H8 F3 N O2
Molecular Weight:267.207
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00699135
Wikidata:Q82629900
Mol file:847446-88-2.mol

Synonyms:847446-88-2;4-(3-(TRIFLUOROMETHYL)PYRIDIN-2-YL)BENZOIC ACID;4-[3-(Trifluoromethyl)pyridin-2-yl]benzoic acid;Benzoic acid,4-[3-(trifluoromethyl)-2-pyridinyl]-;SCHEMBL3881337;DTXSID00699135;AKOS015966562;4-(3-Trifluoromethylpyridin-2-yl)benzoic acid;4-(3-trifluoromethylpyridine-2-yl)benzoic acid;4-(3-Trifluoromethyl-pyridin-2-yl)-benzoic acid;4-(3-(TRIFLUOROMETHYL)(PYRIDIN-2-YL))BENZOIC ACID

Suppliers and Price of 4-(3-(Trifluoromethyl)pyridin-2-YL)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(3-(Trifluoromethyl)pyridin-2-YL)benzoic acid

Chemical Property:

PSA：50.19000
LogP:3.46560
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:267.05071298
Heavy Atom Count:19
Complexity:324

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(N=C1)C2=CC=C(C=C2)C(=O)O)C(F)(F)F

Technology Process of 4-(3-(Trifluoromethyl)pyridin-2-YL)benzoic acid

There total 5 articles about 4-(3-(Trifluoromethyl)pyridin-2-YL)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 847446-88-2
4-(3-trifluoromethylpyridin-2-yl)benzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; for 18h; Heating;

Reference yield:

: C₁₄H₁₀F₃NO₂

: 847446-88-2
4-(3-trifluoromethylpyridin-2-yl)benzoic acid

Guidance literature:: With potassium hydroxide; water; In tetrahydrofuran; for 0.166667h; Heating / reflux;

Reference yield:

: 847446-85-9
4-(3-(trifluoromethyl)pyridin-2-yl)benzaldehyde

: 847446-88-2
4-(3-trifluoromethylpyridin-2-yl)benzoic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In water; tert-butyl alcohol; at 20 ℃; for 2h;
DOI:10.1016/j.bmcl.2004.11.033