4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde

Base Information

• Chemical Name: 4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde
• CAS No.: 847446-85-9
• Molecular Formula: C13H8 F3 N O
• Molecular Weight: 251.208
• Hs Code.: 2933399090
• Mol file: 847446-85-9.mol

Synonyms:4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde;4-(5-Methylpyridin-2-yl)benzaldehyde;4-(6-Methylpyridin-2-yl)benzaldehyde

Chemical Property of 4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde

Chemical Property:

• Melting Point: 67～68℃
• PSA: 29.96000
• LogP: 3.57990

Purity/Quality:

97% ^*data from raw suppliers

4-[3-(Trifluoromethyl)-2-pyridinyl]-benzenecarbaldehyde >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde

There total 4 articles about 4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-(p-tolyl)-3-(trifluoromethyl)pyridine (573676-03-6) → 4-(3-(trifluoromethyl)pyridin-2-yl)benzaldehyde (847446-85-9)

Guidance literature:

2-(p-tolyl)-3-(trifluoromethyl)pyridine; With selenium(IV) oxide; In 1,4-dioxane; Reflux;

With sodium hydrogencarbonate; In 1,4-dioxane; at 25 ℃;

Reference yield: 85.0%

→ 4-(3-(trifluoromethyl)pyridin-2-yl)benzaldehyde (847446-85-9)

Guidance literature:

Reference yield:

4-methylphenylboronic acid (5720-05-8) + 2-chloro-3-trifluoromethyl-pyridine (65753-47-1) → 4-(3-(trifluoromethyl)pyridin-2-yl)benzaldehyde (847446-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol; water / Reflux

2.1: selenium(IV) oxide / 1,4-dioxane / Reflux

2.2: 25 °C

With selenium(IV) oxide; sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; water;

upstream raw materials:

4-formylphenylboronic acid,

4-methylphenylboronic acid

2-chloro-3-trifluoromethyl-pyridine

2-(p-tolyl)-3-(trifluoromethyl)pyridine

Downstream raw materials:

4-(3-trifluoromethylpyridin-2-yl)benzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 847446-85-9 4-(3-(Trifluoromethyl)pyridin-2-yl)benzaldehyde

Send

Send

Metric Ton KG G Pound L ML

Send

Send