(+)-2,2-dimethyl-1,3-butanediol dibenzoate

Base Information

• Chemical Name: (+)-2,2-dimethyl-1,3-butanediol dibenzoate
• CAS No.: 1372861-84-1
• Molecular Formula: C₂₀H₂₂O₄
• Molecular Weight: 326.392
• Mol file: 1372861-84-1.mol

Synonyms:(+)-2,2-dimethyl-1,3-butanediol dibenzoate

Chemical Property of (+)-2,2-dimethyl-1,3-butanediol dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (+)-2,2-dimethyl-1,3-butanediol dibenzoate

There total 1 articles about (+)-2,2-dimethyl-1,3-butanediol dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-hydroxy-3,3-dimethyl-butan-2-one (1823-90-1) + benzaldehyde (100-52-7) + benzoyl chloride (98-88-4) → (+)-2,2-dimethyl-1,3-butanediol dibenzoate (1372861-84-1)

Guidance literature:

4-hydroxy-3,3-dimethyl-butan-2-one; benzaldehyde; With dilithium (R)-3,3'-diphenylbinaphtholate; In tetrahydrofuran; hexane; at -40 ℃; for 6h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; hexane; water; at 20 ℃; for 0.166667h;

benzoyl chloride; With dmap; triethylamine; at 20 ℃; for 12h; optical yield given as %ee; enantioselective reaction;

DOI:10.3390/molecules16065008

upstream raw materials:

4-hydroxy-3,3-dimethyl-butan-2-one

benzaldehyde

benzoyl chloride

Refernces