benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle

Base Information

• Chemical Name: benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle
• CAS No.: 126717-86-0
• Molecular Formula: C₄₀H₃₈O₇
• Molecular Weight: 630.738
• Mol file: 126717-86-0.mol

Synonyms:benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle

Chemical Property of benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle

There total 1 articles about benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(((5-methyl-1,3-phenylene)bis(oxy))bis(methylene))dibenzene (36776-43-9) + 2-benzyloxy-5-methoxycarbonyl-4-methoxy-3,6-dimethylbenzoic acid (78023-67-3) → benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle (126717-86-0)

Guidance literature:

With trifluoroacetic anhydride; In dichloromethane; for 4h; Ambient temperature;

DOI:10.1002/hlca.19890720524

Reference yield: 87.0%

benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle (126717-86-0) → hydroxy-4-(dihydroxy-2',4'-methyl-6'-benzoyl)-3-methoxy-6-dimethyl-2,5-benzoate de methyle (126717-87-1)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethyl acetate;

DOI:10.1002/hlca.19890720524

Reference yield:

benzyloxy-4--3-methoxy-6-dimethyl-2,5-benzoate de methyle (126717-86-0) → acide -6-formyl-3-hydroxy-4-methyl-2-benzoique (126739-88-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 87 percent / hydrogen, conc. HCl / 10percent Pd/C / ethyl acetate

2: 75 percent / K₃, K₂CO₃ / H₂O / 0.17 h

3: hexamethylenetetramine / 1.) reflux, 24h, 2.) water, 60 deg C, 5h

4: 35 percent / BCl₃ / CH₂Cl₂ / 6 h / Ambient temperature

With hydrogenchloride; hexamethylenetetramine; hydrogen; boron trichloride; potassium carbonate; potassium hexacyanoferrate(III); palladium on activated charcoal; In dichloromethane; water; ethyl acetate;

DOI:10.1002/hlca.19890720524

upstream raw materials:

(((5-methyl-1,3-phenylene)bis(oxy))bis(methylene))dibenzene

2-benzyloxy-5-methoxycarbonyl-4-methoxy-3,6-dimethylbenzoic acid

Downstream raw materials:

hydroxy-4-(dihydroxy-2',4'-methyl-6'-benzoyl)-3-methoxy-6-dimethyl-2,5-benzoate de methyle

acide -6-formyl-3-hydroxy-4-methyl-2-benzoique

Refernces