(S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate

Base Information

• Chemical Name: (S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate
• CAS No.: 221310-60-7
• Molecular Formula: C₁₆H₁₇NO₆S
• Molecular Weight: 351.38
• Mol file: 221310-60-7.mol

Synonyms:(S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate

Chemical Property of (S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate

There total 1 articles about (S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

(2S)-1-(benzyloxy)propan-2-ol (13807-91-5,89401-28-5,103129-25-5,85483-97-2) + 4-Nitrobenzenesulfonyl chloride (98-74-8) → (S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate (221310-60-7)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; at -30 - 20 ℃;

DOI:10.1016/S0040-4020(98)01128-4

Reference yield:

(S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate (221310-60-7) → (R)-(2-benzyloxy-1-methyl)ethyl phenyl ether (221310-61-8) + (S)-(2-benzyloxy-1-methyl)ethyl phenyl ether

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 32h; Product distribution; Heating; other solvent, temperature, reaction time;

DOI:10.1016/S0040-4020(98)01128-4

Reference yield:

(S)-(+)-(2-benzyloxy-1-methyl)ethyl 4-nitrobenzenesulfonate (221310-60-7) → (S)-2-Methyl-2-phenoxy carbinolcid (87860-35-3) + (R)-2-phenoxypropan-1-ol (64658-22-6)

Guidance literature:

With palladium on activated charcoal; hydrogen; potassium carbonate; Product distribution; Heating; multistep reaction; various solvents, temperatures, reaction times;

DOI:10.1016/S0040-4020(98)01128-4

upstream raw materials:

(2S)-1-(benzyloxy)propan-2-ol

4-Nitrobenzenesulfonyl chloride

Downstream raw materials:

(S)-2-Methyl-2-phenoxy carbinolcid

(R)-2-phenoxypropan-1-ol

(R)-(2-benzyloxy-1-methyl)ethyl phenyl ether