Technology Process of benzyl 5-bromo-2-[(4-methoxyphenyl)ethynyl]phenylcarbamate
There total 6 articles about benzyl 5-bromo-2-[(4-methoxyphenyl)ethynyl]phenylcarbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(l) iodide; trifuran-2-yl-phosphane; diisopropylamine; palladium dichloride;
In
toluene;
at 55 ℃;
chemoselective reaction;
Inert atmosphere;
DOI:10.1016/j.tetlet.2011.05.040
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium azide / acetone / 0.17 h / 20 °C / Inert atmosphere
2: toluene / 3.5 h / 80 - 85 °C / Inert atmosphere
3: dmap / toluene / 1 h / 80 - 85 °C / Inert atmosphere
4: copper(l) iodide; trifuran-2-yl-phosphane; diisopropylamine; palladium dichloride / toluene / 55 °C / Inert atmosphere
With
dmap; copper(l) iodide; sodium azide; trifuran-2-yl-phosphane; diisopropylamine; palladium dichloride;
In
acetone; toluene;
2: Curtius rearrangement / 4: Sonogashira coupling;
DOI:10.1016/j.tetlet.2011.05.040
- Guidance literature:
-
Multi-step reaction with 3 steps
1: toluene / 3.5 h / 80 - 85 °C / Inert atmosphere
2: dmap / toluene / 1 h / 80 - 85 °C / Inert atmosphere
3: copper(l) iodide; trifuran-2-yl-phosphane; diisopropylamine; palladium dichloride / toluene / 55 °C / Inert atmosphere
With
dmap; copper(l) iodide; trifuran-2-yl-phosphane; diisopropylamine; palladium dichloride;
In
toluene;
1: Curtius rearrangement / 3: Sonogashira coupling;
DOI:10.1016/j.tetlet.2011.05.040
