(piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

Base Information

Chemical Name:(piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride
CAS No.:1415971-15-1
Molecular Formula:C₂₀H₂₉NO₃*ClH
Molecular Weight:367.916
Hs Code.:

Synonyms:(piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

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Chemical Property of (piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

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Technology Process of (piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

There total 3 articles about (piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1415971-14-0
tert-butyl 4-((2-cyclohexyl-2-hydroxy-2-phenylacetyloxy)methyl)piperidine-1-carboxylate

: 1415971-15-1
(piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 4335-77-7,20585-34-6,20585-39-1,50896-04-3
cyclohexylmandelic acid

: 1415971-15-1
(piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C

2: hydrogenchloride / dichloromethane; 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 158407-04-6
tert-butyl 4-(bromomethyl)piperidine-1-carboxylate

: 1415971-15-1
(piperidin-4-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 72 h / 20 °C

2: hydrogenchloride / dichloromethane; 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;