Technology Process of methyl 3-(2-phenylbenzoxazol-5-yl)-2-chloropropionate
There total 5 articles about methyl 3-(2-phenylbenzoxazol-5-yl)-2-chloropropionate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(I) oxide; hydrogenchloride; sodium nitrite;
Yield given. Multistep reaction;
1.) acetone, 10 min, 2.) acetone, 35 deg C, 20 min;
DOI:10.1248/cpb.45.1984
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Pb(OAc)4 / benzene / 0.5 h / Ambient temperature
2: 91 percent / H2, AcOH / 10percent Pd/C / 1.5 h / 760 Torr / Ambient temperature
3: 1.) aq. NaNO2, conc. HCl, 2.) Cu2O / 1.) acetone, 10 min, 2.) acetone, 35 deg C, 20 min
With
copper(I) oxide; lead(IV) acetate; hydrogenchloride; hydrogen; acetic acid; sodium nitrite;
palladium on activated charcoal;
In
benzene;
DOI:10.1248/cpb.45.1984
- Guidance literature:
-
Multi-step reaction with 4 steps
1: ethanol / 1.3 h / Heating
2: Pb(OAc)4 / benzene / 0.5 h / Ambient temperature
3: 91 percent / H2, AcOH / 10percent Pd/C / 1.5 h / 760 Torr / Ambient temperature
4: 1.) aq. NaNO2, conc. HCl, 2.) Cu2O / 1.) acetone, 10 min, 2.) acetone, 35 deg C, 20 min
With
copper(I) oxide; lead(IV) acetate; hydrogenchloride; hydrogen; acetic acid; sodium nitrite;
palladium on activated charcoal;
In
ethanol; benzene;
DOI:10.1248/cpb.45.1984
