1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

Base Information

Chemical Name:1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene
CAS No.:129122-41-4
Molecular Formula:C₂₂H₁₈Br₂FN
Molecular Weight:475.198
Hs Code.:

Synonyms:1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

Suppliers and Price of 1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

There total 7 articles about 1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 558-13-4
carbon tetrabromide

: 128108-47-4
4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinecarboxaldehyde

: 129122-41-4
1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

Guidance literature:: With sodium hydrogencarbonate; triphenylphosphine; SiO₂; In hexane; dichloromethane;

Reference yield:

: 1608-51-1
4-fluorochalcone

: 129122-41-4
1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

Guidance literature:: Multi-step reaction with 5 steps

1: EtONa / ethanol / 4.5 h / Ambient temperature

2: NH₄OAc, Cu(OAc)2 / acetic acid / 24 h / Heating

3: LiAlH₄ / tetrahydrofuran / 6 h / Ambient temperature

4: 87 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / Ambient temperature

5: triphenylphosphine / CH₂Cl₂ / 0.42 h / Ambient temperature

With lithium aluminium tetrahydride; copper diacetate; ammonium acetate; sodium ethanolate; Dess-Martin periodane; triphenylphosphine; In tetrahydrofuran; ethanol; dichloromethane; acetic acid;
DOI:10.1021/jm00113a019

Reference yield:

: 122253-00-3
4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinemethanol

: 129122-41-4
1,1-Dibromo-2-(4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenylpyridin-3-yl)ethene

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.5 h / Ambient temperature

2: triphenylphosphine / CH₂Cl₂ / 0.42 h / Ambient temperature

With Dess-Martin periodane; triphenylphosphine; In dichloromethane;
DOI:10.1021/jm00113a019