S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

Base Information

Chemical Name:S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate
CAS No.:1170733-34-2
Molecular Formula:C₂₂H₂₄FNO₅S
Molecular Weight:433.501
Hs Code.:

Synonyms:S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

Suppliers and Price of S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

There total 6 articles about S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 530-62-1
1,1'-carbonyldiimidazole

: 61869-08-7
paroxetine

: 60-24-2
2-hydroxyethanethiol

: 74-88-4
methyl iodide

: 1170733-34-2
S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

: C₂₂H₂₄FNO₅S

Guidance literature:: 1,1'-carbonyldiimidazole; paroxetine; With triethylamine; In dichloromethane; at 20 ℃;

methyl iodide; In tetrahydrofuran; at 0 - 20 ℃;

2-hydroxyethanethiol; In acetonitrile; at 0 - 20 ℃; for 24h; Product distribution / selectivity;

Reference yield: 60.0%

: 75-44-5
phosgene

: 61869-08-7
paroxetine

: 60-24-2
2-hydroxyethanethiol

: 1170733-34-2
S-(2-hydroxyethyl) (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine-1-carbothioate

: C₂₂H₂₄FNO₅S

Guidance literature:: phosgene; paroxetine; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h;

2-hydroxyethanethiol; In dichloromethane; at 0 - 20 ℃; Product distribution / selectivity;