(R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester

Base Information

• Chemical Name: (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester
• CAS No.: 848865-01-0
• Molecular Formula: C₂₀H₂₄ClFN₂O₇S
• Molecular Weight: 490.937

Synonyms:(R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester

Chemical Property of (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester

There total 1 articles about (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

carbonochloridic acid 1-chloro-ethyl ester (50893-53-3) + (S)-(-)-N-[[3-[3-fluoro-4-(tetrahydro-2H-thiopyran-4-yl)phenyl]-2-oxo-5-oxaolidinyl]methyl]acetamide S,S-dioxide (188974-61-0) → (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester (848865-01-0)

Guidance literature:

(S)-(-)-N-[[3-[3-fluoro-4-(tetrahydro-2H-thiopyran-4-yl)phenyl]-2-oxo-5-oxaolidinyl]methyl]acetamide S,S-dioxide; With lithium tert-butoxide; In hexane; dichloromethane; acetonitrile; at 0 - 20 ℃; for 0.416667h;

carbonochloridic acid 1-chloro-ethyl ester; at 0 - 20 ℃; for 0.166667h;

Reference yield: 67.0%

(R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester (848865-01-0) + cesium propionate (38869-24-8) → propionic acid 1-(acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamoyloxy)-ethyl ester

Guidance literature:

With sodium iodide; In acetonitrile; Heating / reflux;

Reference yield: 63.0%

cesium cyclopentanecarboxylate (848865-34-9) + (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester (848865-01-0) → cyclopentanecarboxylic acid 1-(acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ6-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamoyloxy)-ethyl ester

Guidance literature:

With sodium iodide; In acetonitrile; Heating / reflux;

upstream raw materials:

carbonochloridic acid 1-chloro-ethyl ester

(S)-(-)-N-[[3-[3-fluoro-4-(tetrahydro-2H-thiopyran-4-yl)phenyl]-2-oxo-5-oxaolidinyl]methyl]acetamide S,S-dioxide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 848865-01-0 (R)-acetyl-{3-[4-(1,1-dioxo-hexahydro-1λ⁶-thiopyran-4-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5(R)-ylmethyl}-carbamic acid 1(R,S)-chloroethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send