(R)-1-phenylethylpyridinium chloride

Base Information

• Chemical Name: (R)-1-phenylethylpyridinium chloride
• CAS No.: 120343-60-4
• Molecular Formula: C₁₃H₁₄N*Cl
• Molecular Weight: 219.714
• Mol file: 120343-60-4.mol

Synonyms:(R)-1-phenylethylpyridinium chloride

Chemical Property of (R)-1-phenylethylpyridinium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-phenylethylpyridinium chloride

There total 1 articles about (R)-1-phenylethylpyridinium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(R)-1-phenyl-ethyl-amine (3886-69-9) + 1-(2,4-dinitrophenyl)-pyridinium chloride (4185-69-7) → (R)-1-phenylethylpyridinium chloride (120343-60-4)

Guidance literature:

In butan-1-ol; for 24h; Heating;

DOI:10.3390/12081940

Reference yield: 67.0%

(R)-1-phenylethylpyridinium chloride (120343-60-4) → (+)-1-<(1R)-1-phenylethyl>-1,4-dihydropyridine

Guidance literature:

With sodium dithionite; potassium carbonate; In water; toluene; at 100 ℃; for 0.2h;

DOI:10.1016/S0040-4039(00)75796-0

Reference yield: 46.0%

methylmagnesium chloride (676-58-4) + (R)-1-phenylethylpyridinium chloride (120343-60-4) → (1R,2R)-(-)-2-methyl-1-(1-phenylethyl)-1,2,5,6-tetrahydropyridine + (1R,2S)-(+)-2-methyl-1-(1-phenylethyl)-1,2,5,6-tetrahydropyridine

Guidance literature:

methylmagnesium chloride; (R)-1-phenylethylpyridinium chloride; In tetrahydrofuran; toluene; at -20 - 0 ℃; for 3h;

With sodium tetrahydroborate; In methanol; water; for 1h; Further stages.; Heating;

DOI:10.1002/(SICI)1099-0690(200004)2000:8<1391::AID-EJOC1391>3.0.CO;2-D

upstream raw materials:

(R)-1-phenyl-ethyl-amine

1-(2,4-dinitrophenyl)-pyridinium chloride

Downstream raw materials:

(R)-N¹-α-methylbenzyl-1,2-DHP

(S)-coniine hydrochloride

(1'R,2R)-(-)-1-(1-phenylethyl)-2-propylpiperidine