phenylacetic acid dicyclohexylamide

Base Information

• Chemical Name: phenylacetic acid dicyclohexylamide
• CAS No.: 77383-21-2
• Molecular Formula: C₂₀H₂₉NO
• Molecular Weight: 299.456
• Mol file: 77383-21-2.mol

Synonyms:phenylacetic acid dicyclohexylamide

Chemical Property of phenylacetic acid dicyclohexylamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of phenylacetic acid dicyclohexylamide

There total 2 articles about phenylacetic acid dicyclohexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

carbon monoxide (201230-82-2) + N,N-dicyclohexylbenzylamine → phenylacetic acid dicyclohexylamide (77383-21-2)

Guidance literature:

N,N-dicyclohexylbenzylamine; With ortho-diphenylphosphinobenzoic acid; nickel dichloride; for 0.5h; Glovebox; Autoclave;

carbon monoxide; With iodine; at 140 ℃; for 18h; under 7600.51 Torr; Glovebox; Autoclave;

DOI:10.1021/acs.orglett.7b01488

Reference yield:

N-cyclohexyl-cyclohexanamine (101-83-7) + phenylacetyl chloride (103-80-0) → phenylacetic acid dicyclohexylamide (77383-21-2)

Guidance literature:

Reference yield: 92.0%

phenylacetic acid dicyclohexylamide (77383-21-2) + benzylidene phenylamine (538-51-2) → N,N-dicyclohexyl-2,3-diphenyl-3-phenylamino-propionamide

Guidance literature:

phenylacetic acid dicyclohexylamide; With lithium diisopropyl amide; In tetrahydrofuran; at 20 ℃; for 0.25h;

benzylidene phenylamine; In tetrahydrofuran; at 22 ℃; for 1h;

upstream raw materials:

N-cyclohexyl-cyclohexanamine

phenylacetyl chloride

carbon monoxide

Downstream raw materials:

α-(4-Chlorbenzyl)-phenylessigsaeure-N,N-dicyclohexylamid

(2S,3S)-2,3-Diphenyl-pentanedioic acid 1-dicyclohexylamide 5-dimethylamide

(2S,3R)-2,3-Diphenyl-pentanedioic acid 1-dicyclohexylamide 5-dimethylamide

N,N-Dicyclohexyl-2-phenyl-thioacetamide