Benzenemethanol, 3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]-

Base Information

Chemical Name:Benzenemethanol, 3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]-
CAS No.:1620579-55-6
Molecular Formula:C₁₃H₈F₅NO₂
Molecular Weight:305.204
Hs Code.:
Mol file:1620579-55-6.mol

Synonyms:(3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)phenyl)methanol

Suppliers and Price of Benzenemethanol, 3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenemethanol, 3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]-

Chemical Property:

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Technology Process of Benzenemethanol, 3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]-

There total 5 articles about Benzenemethanol, 3,5-difluoro-4-[[2-(trifluoromethyl)-4-pyridinyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1620579-54-5
3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)benzaldehyde

: 1620579-55-6
(3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)phenyl)methanol

Guidance literature:: With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 1h; Temperature; Time;

Reference yield:

: 170886-13-2
4-hydroxy-2-trifluoromethylpyridine

: 1620579-55-6
(3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)phenyl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 100 °C / Inert atmosphere

2: methanol; sodium tetrahydroborate / 1 h / 0 - 20 °C

With methanol; sodium tetrahydroborate; potassium carbonate; In N,N-dimethyl-formamide;

Reference yield:

: 132123-54-7
3,4,5-trifluorobenzaldehyde

: 1620579-55-6
(3,5-difluoro-4-((2-(trifluoromethyl)pyridin-4-yl)oxy)phenyl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 18 h / 70 °C

2: methanol; sodium tetrahydroborate / 0.17 h / 0 °C

With methanol; sodium tetrahydroborate; potassium carbonate; In acetonitrile;