(2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Base Information

Chemical Name:(2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol
CAS No.:135245-91-9
Molecular Formula:C₁₉H₃₄O₄Si
Molecular Weight:354.562
Hs Code.:

Synonyms:(2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Suppliers and Price of (2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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MSDS Files:

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Technology Process of (2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

There total 6 articles about (2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 135245-91-9
(2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / EtN(i-Pr)2 / CH₂Cl₂ / Ambient temperature

2: 1) O₃, 2) Me₂S / 1) CH₂Cl₂/MeOH, -78 deg C, 2) room temp., 5 h

3: tetrahydrofuran / -78 °C / other methyl-metal compounds, solvents, temperatures

With dimethylsulfide; ozone; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)97081-3

Reference yield:

: 226926-94-9
Acetic acid (E)-(R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-methyl-hex-3-enyl ester

: 135245-91-9
(2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Guidance literature:: Multi-step reaction with 4 steps

1: 0.1 N KOH/MeOH

2: 86 percent / EtN(i-Pr)2 / CH₂Cl₂ / Ambient temperature

3: 1) O₃, 2) Me₂S / 1) CH₂Cl₂/MeOH, -78 deg C, 2) room temp., 5 h

4: tetrahydrofuran / -78 °C / other methyl-metal compounds, solvents, temperatures

With methanol; potassium hydroxide; dimethylsulfide; ozone; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)97081-3

Reference yield:

: 138513-53-8
(R)-(E)-2-<<(tert-Butyldimethylsilyl)oxy>methyl>-5-methylhex-3-en-1-ol

: 135245-91-9
(2R,3R)-3-Benzyloxymethoxymethyl-4-(tert-butyl-dimethyl-silanyloxy)-butan-2-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / EtN(i-Pr)2 / CH₂Cl₂ / Ambient temperature

2: 1) O₃, 2) Me₂S / 1) CH₂Cl₂/MeOH, -78 deg C, 2) room temp., 5 h

3: tetrahydrofuran / -78 °C / other methyl-metal compounds, solvents, temperatures

With dimethylsulfide; ozone; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/S0040-4039(00)97081-3