4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

Base Information

Chemical Name:4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine
CAS No.:1262414-36-7
Molecular Formula:C₂₉H₃₁N₃O₃
Molecular Weight:469.583
Hs Code.:

Synonyms:4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

Suppliers and Price of 4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

There total 14 articles about 4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5398-44-7
2,6-dichloropyridine-4-carboxylic acid

: 1262414-36-7
4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium hydroxide; methanol / water / 4 h / 34 - 70 °C

1.2: 20 °C

2.1: sulfuric acid / methanol / 24 h / Reflux

3.1: bis[1,2-bis(diphenylphosphino)ferrocene]-palladium⁽⁰⁾ / water; tetrahydrofuran / 3 h / 85 °C / Inert atmosphere

4.1: hydrogenchloride; sodium hydroxide / ethanol; water / 0.5 h / 90 °C

5.1: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 2 h / 20 °C

6.1: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 25 h / 20 °C / 750.08 Torr

7.1: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 1 h / 20 °C

7.2: 0.25 h / 110 °C / Microwave irradiation

With hydrogenchloride; methanol; sulfuric acid; hydrogen; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; bis[1,2-bis(diphenylphosphino)ferrocene]-palladium⁽⁰⁾; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;

Reference yield:

: 42521-10-8
2-chloro-6-methoxyisonicotinic acid methyl ester

: 1262414-36-7
4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: bis[1,2-bis(diphenylphosphino)ferrocene]-palladium⁽⁰⁾ / water; tetrahydrofuran / 3 h / 85 °C / Inert atmosphere

2.1: hydrogenchloride; sodium hydroxide / ethanol; water / 0.5 h / 90 °C

3.1: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 2 h / 20 °C

4.1: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 25 h / 20 °C / 750.08 Torr

5.1: N-ethyl-N,N-diisopropylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / dichloromethane / 1 h / 20 °C

5.2: 0.25 h / 110 °C / Microwave irradiation

With hydrogenchloride; hydrogen; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; bis[1,2-bis(diphenylphosphino)ferrocene]-palladium⁽⁰⁾; palladium 10% on activated carbon; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;