(R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

Base Information

Chemical Name:(R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester
CAS No.:163215-96-1
Molecular Formula:C₁₇H₂₈O₂
Molecular Weight:264.408
Hs Code.:

Synonyms:(R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

Suppliers and Price of (R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

There total 1 articles about (R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 18951-85-4,57030-77-0
(R)-citronellic acid

: 18890-22-7,54423-21-1
(R)-3-methylcyclohex-2-en-1-ol

: 163215-96-1
(R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 18h;
DOI:10.1021/jm980736v

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 163215-96-1
(R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

: tert-Butyl-[(Z)-(R)-3,7-dimethyl-1-((R)-3-methyl-cyclohex-2-enyloxy)-octa-1,6-dienyloxy]-dimethyl-silane

Guidance literature:: (R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester; With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - -50 ℃; for 0.5h;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; hexane; for 0.333333h;
DOI:10.1021/jm980736v

Reference yield:

: 163215-96-1
(R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester

: 163215-98-3
(2R,3R)-3,7-dimethyl-2((1S)-1-methyl-2-cyclohexenyl)-6-octen-1-ol

: (2S,3R)-3,7-dimethyl-2((1S)-1-methyl-2-cyclohexenyl)-6-octen-1-ol

Guidance literature:: (R)-3,7-Dimethyl-oct-6-enoic acid (R)-3-methyl-cyclohex-2-enyl ester; With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 - -50 ℃; for 0.5h;

With tert-butyldimethylsilyl chloride; In tetrahydrofuran; hexane; at -50 ℃; for 0.5h; Overall yield = 60 %; Overall yield = 2.03 g; Optical yield = 83.333 %de; diastereoselective reaction; Further stages;
DOI:10.1021/acs.orglett.7b02350