Technology Process of (-)-1-O-acetyl-3-O-benzylpropane-1,2,3-triol
There total 9 articles about (-)-1-O-acetyl-3-O-benzylpropane-1,2,3-triol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydroxide; tetrabutylammonium hydrogen sulfate / CH2Cl2; H2O / 25 h / 50 °C
2: 11.74 g / Amberlyst 15 / methanol / 5 h / 20 °C
3: Pseudomonas cepacia lipase / tetrahydrofuran; hexane
With
sodium hydroxide; Amberlyst 15; Pseudomonas cepacia lipase; tetra(n-butyl)ammonium hydrogensulfate;
In
tetrahydrofuran; methanol; hexane; dichloromethane; water;
DOI:10.1016/j.tetasy.2004.07.040
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 11.74 g / Amberlyst 15 / methanol / 5 h / 20 °C
2: Pseudomonas cepacia lipase / tetrahydrofuran; hexane
With
Amberlyst 15; Pseudomonas cepacia lipase;
In
tetrahydrofuran; methanol; hexane;
DOI:10.1016/j.tetasy.2004.07.040
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 52 percent / NaH / tetrahydrofuran
2: 3M aq. HCl
3: 92 percent / Et3N; DMAP / ethyl acetate / 1.5 h / 20 °C
4: baker's yeast; glucose / aq. phosphate buffer; ethanol; dimethylsulfoxide / 4 h / pH 7
With
hydrogenchloride; dmap; baker's yeast; D-glucose; sodium hydride; triethylamine;
In
tetrahydrofuran; phosphate buffer; ethanol; dimethyl sulfoxide; ethyl acetate;
1: Alkylation / 2: Hydrolysis / 3: Acetylation / 4: Reduction;
DOI:10.1016/S0957-4166(99)00415-2
