3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester

Base Information

• Chemical Name: 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester
• CAS No.: 1442447-48-4
• Molecular Formula: C₆H₃Br₂NO₄
• Molecular Weight: 312.902
• Mol file: 1442447-48-4.mol

Synonyms:3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester

Chemical Property of 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester

Chemical Property:

• Boiling Point: 290.2±50.0 °C(Predicted)
• Density: 2.437±0.06 g/cm3(Predicted)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Use Description: 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester is a chemical compound with diverse potential applications across different fields. In the pharmaceutical industry, it can serve as an intermediate or building block in the synthesis of pharmaceutical compounds, contributing to drug development and manufacturing processes. Its structural properties make it valuable for creating complex molecules with specific pharmacological activities. In organic chemistry research, it acts as a versatile building block for the development of new organic materials, catalysts, and specialty chemicals. Additionally, in academic and industrial laboratories, 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester may be utilized as a reference material for analytical purposes and as a substrate for investigating reaction mechanisms, fostering innovation in the field of synthetic chemistry. While specific uses may vary, its primary significance lies in pharmaceuticals, organic synthesis, and chemical research, playing a crucial role in advancing drug discovery and organic chemistry research.

Technology Process of 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester

There total 1 articles about 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-dibromomaleimide (1122-10-7) + methyl chloroformate (79-22-1) → 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester (1442447-48-4)

Guidance literature:

With 4-methyl-morpholine; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.polymer.2016.01.020

Reference yield: 99.0%

4-aminobenzenemethanol (623-04-1) + 3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester (1442447-48-4) → 3,4-dibromo-1-(4-hydroxymethyl-phenyl)-pyrrole-2,5-dione (1442447-57-5)

Guidance literature:

In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2013.04.088

Reference yield: 86.0%

3,4-dibromo-2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid methyl ester (1442447-48-4) + benzylamine (100-46-9) → N-benzyl-2,3-dibromo-maleimide (91026-00-5)

Guidance literature:

In dichloromethane; at 20 ℃; for 0.333333h;

DOI:10.1016/j.tetlet.2013.04.088

upstream raw materials:

2,3-dibromomaleimide

methyl chloroformate

Downstream raw materials:

N-cyclohexyl-3,4-dibromomaleimide

N-benzyl-2,3-dibromo-maleimide

N-(p-fluorobenzyl)-3,4-dibromomaleimide

3,4-dibromo-2,5-dihydro-1-phenyl-1H-pyrrole-2,5-dione