1'-(Aminocarbonyl)-1,2,3,4,5-pentaphenyl-ferrocene

Base Information

• Chemical Name: 1'-(Aminocarbonyl)-1,2,3,4,5-pentaphenyl-ferrocene
• CAS No.: 894777-14-1
• Molecular Formula: C41H31 Fe N O
• Molecular Weight: 609.547
• Mol file: 894777-14-1.mol

Synonyms:1’-(Aminocarbonyl)-1,2,3,4,5-pentaphenyl-ferrocene;1μ,2μ,3μ4μ,5μ-Pentaphenylferrocene carboxamide

Chemical Property of 1'-(Aminocarbonyl)-1,2,3,4,5-pentaphenyl-ferrocene

Chemical Property:

• Melting Point: 245.5-246.0 °C(Solv: water (7732-18-5))
• PSA: 43.09000
• LogP: 7.79880
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1′,2′,3′4′,5′-Pentaphenylferrocene carboxamide ≥98.0% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Reactant for: Asymmetric Aza-Claisen rearrangementSynthesis and diastereoselective ortholithiation / cyclopalladationSynthesis of enantioselective ferrocenyl-imidazoline palladacycle catalysts

Technology Process of 1'-(Aminocarbonyl)-1,2,3,4,5-pentaphenyl-ferrocene

There total 1 articles about 1'-(Aminocarbonyl)-1,2,3,4,5-pentaphenyl-ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2,3,4,5-pentaphenylferrocene-1'-carboxylic acid (323187-44-6) + ammonia (7664-41-7) → (pentaphenylferrocenyl)(CONH2) (894777-14-1)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In methanol; dichloromethane; Fe complex was treated with chloride in CH2Cl2 in presence of DMF (catalyst), then NH3 in methanol at -78°C to room temp.;

DOI:10.1021/om060187o

Reference yield: 77.0%

(pentaphenylferrocenyl)(CONH2) (894777-14-1) + (R,R)-1,2-diphenylethylenediamine (35132-20-8) + p-toluenesulfonyl chloride (98-59-9) → (pentaphenylferrocenyl)(C3N2H2)Ph2SO2(p-Tol)

Guidance literature:

With triethyloxonium fluoroborate; In dichloromethane; 1,2-dichloro-ethane; Et3OBF4, CH2Cl2, room temp.; then amine deriv.; 1,2-dichloroethane; temp. from 0°C to Δ; sulfonyl deriv.; base, CH2Cl2;

DOI:10.1002/anie.200601731

Reference yield: 64.0%

(pentaphenylferrocenyl)(CONH2) (894777-14-1) + (1R,2S)-1-phenyl-N2-methyl-1,2-propandiamine (130827-42-8) → [(C5H4CNCH(C6H5)CH(CH3)NCH3)Fe(C5(C6H5)5)]

Guidance literature:

With triethyloxonium fluoroborate; In dichloromethane; 1,2-dichloro-ethane; Fe complex was treated with Et3OBF4 in CH2Cl2 at room temp.; treated with diamine in dichloroethane at room temp.; heated at 80°C;

DOI:10.1021/om060187o

upstream raw materials:

1,2,3,4,5-pentaphenylferrocene-1'-carboxylic acid

ammonia

Refernces