Technology Process of 1,2,3,4,5-pentaphenylferrocene-1'-carboxylic acid
There total 1 articles about 1,2,3,4,5-pentaphenylferrocene-1'-carboxylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; potassium tert-butylate;
In
1,2-dimethoxyethane;
under N2, Schlenk technique; to soln. of Fe complex KO(t-Bu) and H2O were added, mixt. was refluxed for 1 h, cooled to room temp., acidified with 1 M HCl; ppt. was filtered off, washed with water, dried, suspd. in toluene, residual water was removed, susp. was cooled, ppt. was filtered off, dried in air; elem. anal.;
DOI:10.1021/om0204989
- Guidance literature:
-
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
methanol; dichloromethane;
Fe complex was treated with chloride in CH2Cl2 in presence of DMF (catalyst), then NH3 in methanol at -78°C to room temp.;
DOI:10.1021/om060187o
- Guidance literature:
-
With
oxalyl dichloride; tetrabutylammomium bromide; N,N-dimethyl-formamide;
In
dichloromethane;
under N2, Schlenk technique; to soln. of Fe complex (COCl)2 was added followed by a drop of DMF, mixt. was stirred for 3 h, solvent was removed,residue was dissolved in CH2Cl2, Bu4NBr was added, then NaN3, mixt. was stirred for 18 h; water was added, org. layer was sepd., aq. layer was extd. with CH2Cl2, org. layers were dried (MgSO4), filtered, solvent was removed, residue was chromd. (CH2Cl2/petroleum ether); elem. anal.;
DOI:10.1021/om0204989
