(2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Base Information

Chemical Name:(2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide
CAS No.:909281-86-3
Molecular Formula:C₁₈H₂₄N₂O₃
Molecular Weight:316.4
Hs Code.:

Synonyms:(2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Suppliers and Price of (2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

There total 3 articles about (2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 909281-82-9
(E)-3-(3-methoxy-4-(tetrahydropyran-2-yloxy)phenyl)acrylaldehyde

: 143-33-9,25596-52-5
sodium cyanide

: 124-40-3
dimethyl amine

: 909281-86-3
(2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Guidance literature:: With sodium hydrogensulfite; In methanol; water; at 20 ℃;
DOI:10.1002/ejoc.200600135

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 909281-86-3
(2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 24 h / 20 °C

2: 90 percent / NaHSO₃ / H₂O; methanol / 20 °C

With pyridinium p-toluenesulfonate; sodium hydrogensulfite; In methanol; dichloromethane; water;
DOI:10.1002/ejoc.200600135

Reference yield:

: 458-36-6
trans-coniferyl aldehyde

: 909281-86-3
(2E)-α-(dimethylamino)-3-{3-methoxy-4-[(tetrahydropyran-2-yl)oxy]phenyl}-2-propenyl cyanide

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / pyridinium p-toluenesulfonate / CH₂Cl₂ / 24 h / 20 °C

2: 90 percent / NaHSO₃ / H₂O; methanol / 20 °C

With pyridinium p-toluenesulfonate; sodium hydrogensulfite; In methanol; dichloromethane; water;
DOI:10.1002/ejoc.200600135