1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI)

Base Information

Chemical Name:1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI)
CAS No.:805246-31-5
Molecular Formula:C₁₄H₁₉NO
Molecular Weight:217.311
Hs Code.:
Mol file:805246-31-5.mol

Synonyms:1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI)

Suppliers and Price of 1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI)

Chemical Property:

PSA：12.47000
LogP:2.57210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI)

There total 10 articles about 1H-Benz[g]indole,2,3,3a,4,5,9b-hexahydro-6-methoxy-1-methyl-,(3aR,9bS)-rel-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: tert-butyl (3aS,9bR)-3a-bromo-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[g]indole-1-carboxylate

: 805246-31-5
6-methoxy-1-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[g]indole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 80 ℃; for 36h;
DOI:10.1002/adsc.202000845

Reference yield: 65.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[g]indole

: 805246-31-5
cis-6-methoxy-1-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[g]indole

Guidance literature:: With formic acid; at 90 ℃; for 10h;
DOI:10.1021/jm049782n

Reference yield:

: 33892-75-0
5-Methoxy-1-tetralone

: 805246-31-5
cis-6-methoxy-1-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[g]indole

Guidance literature:: Multi-step reaction with 3 steps

1: LDA

2: H₂ / Raney Ni

3: HCOOH

With formic acid; hydrogen; lithium diisopropyl amide; nickel;
DOI:10.1016/j.farmac.2005.03.010