Technology Process of 3,4-dibenzyloxy-5-(2,3,4-tribenzyloxy-6-benzyloxycarbonylphenoxy)benzoic acid
There total 10 articles about 3,4-dibenzyloxy-5-(2,3,4-tribenzyloxy-6-benzyloxycarbonylphenoxy)benzoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid; tin(ll) chloride;
In
dichloromethane;
at 20 ℃;
for 54h;
DOI:10.1248/cpb.c13-00458
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine / 8 h / 110 °C / Inert atmosphere
2: copper / N,N-dimethyl acetamide / 0.5 h / 160 °C / Inert atmosphere
3: tin(ll) chloride; ethanethiol / dichloromethane / 22 h / 0 - 20 °C
4: potassium carbonate / N,N-dimethyl-formamide / 2 h / 40 °C
5: tin(ll) chloride; acetic acid / dichloromethane / 54 h / 20 °C
With
pyridine; copper; potassium carbonate; acetic acid; ethanethiol; tin(ll) chloride;
In
dichloromethane; N,N-dimethyl acetamide; N,N-dimethyl-formamide;
DOI:10.1248/cpb.c13-00458
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 4.5 h / 100 °C
2: N-Bromosuccinimide / N,N-dimethyl-formamide / 24 h / 20 °C
3: copper / N,N-dimethyl acetamide / 0.5 h / 160 °C / Inert atmosphere
4: tin(ll) chloride; ethanethiol / dichloromethane / 22 h / 0 - 20 °C
5: potassium carbonate / N,N-dimethyl-formamide / 2 h / 40 °C
6: tin(ll) chloride; acetic acid / dichloromethane / 54 h / 20 °C
With
N-Bromosuccinimide; tetra-(n-butyl)ammonium iodide; copper; potassium carbonate; acetic acid; ethanethiol; tin(ll) chloride;
In
dichloromethane; N,N-dimethyl acetamide; N,N-dimethyl-formamide;
DOI:10.1248/cpb.c13-00458
