N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide

Base Information

Chemical Name:N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide
CAS No.:1265885-62-8
Molecular Formula:C₂₉H₂₈ClF₂N₃O
Molecular Weight:508.011
Hs Code.:

Synonyms:N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide

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Chemical Property of N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide

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Technology Process of N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide

There total 1 articles about N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1000698-88-3
(2-amino-4,5-difluoro-phenyl)-carbamic acid tert-butyl ester

: 88333-03-3,10340-91-7
Benzyl isocyanide

: 7499-07-2
4-chloro-2-methylbenzoic acid

: 2043-61-0
cyclohexanecarbaldehyde

: 1265885-62-8
N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide

Guidance literature:: (2-amino-4,5-difluoro-phenyl)-carbamic acid tert-butyl ester; Benzyl isocyanide; 4-chloro-2-methylbenzoic acid; cyclohexanecarbaldehyde; In methanol; at 20 ℃;

With hydrogenchloride; water; In 1,4-dioxane; methanol; at 20 ℃; for 4.5h;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 1265885-62-8
N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide

: C₂₉H₂₇ClF₂N₄O₂

Guidance literature:: N-benzyl-2-[2-(4-chloro-2-methyl-phenyl)-5,6-difluoro-benzoimidazol-1-yl]-2-cyclohexyl-acetamide; With acetic anhydride; acetic acid; sodium nitrite; at 0 - 20 ℃;

With sodium hydrogencarbonate; In water; ethyl acetate;