Technology Process of C28H33Cl3N4O5S2Si
There total 5 articles about C28H33Cl3N4O5S2Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C27H33N3O2Si;
With
tetrakis(triphenylphosphine) palladium(0); 1,3-dimethylbarbituric acid;
In
dichloromethane;
for 8h;
Inert atmosphere;
(2,2,2-trichloroethoxysulfonyl)carbonchloroimidothioic acid methyl ester;
With
sodium carbonate;
In
dichloromethane; water;
for 0.333333h;
Inert atmosphere;
DOI:10.1021/jacs.6b02343
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 14 h / 0 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / dichloromethane; toluene / 2 h / -90 °C / Inert atmosphere
3.1: dichloromethane / 0.33 h / 0 - 20 °C / Inert atmosphere
3.2: 1.67 h / -78 - 20 °C / Inert atmosphere
4.1: 1,3-dimethylbarbituric acid; tetrakis(triphenylphosphine) palladium(0) / dichloromethane / 8 h / Inert atmosphere
4.2: 0.33 h / Inert atmosphere
With
1H-imidazole; tetrakis(triphenylphosphine) palladium(0); 1,3-dimethylbarbituric acid; diisobutylaluminium hydride;
In
dichloromethane; N,N-dimethyl-formamide; toluene;
3.1: |Pictet-Spengler Synthesis / 3.2: |Pictet-Spengler Synthesis;
DOI:10.1021/jacs.6b02343
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: diisobutylaluminium hydride / dichloromethane; toluene / 2 h / -90 °C / Inert atmosphere
2.1: dichloromethane / 0.33 h / 0 - 20 °C / Inert atmosphere
2.2: 1.67 h / -78 - 20 °C / Inert atmosphere
3.1: 1,3-dimethylbarbituric acid; tetrakis(triphenylphosphine) palladium(0) / dichloromethane / 8 h / Inert atmosphere
3.2: 0.33 h / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); 1,3-dimethylbarbituric acid; diisobutylaluminium hydride;
In
dichloromethane; toluene;
2.1: |Pictet-Spengler Synthesis / 2.2: |Pictet-Spengler Synthesis;
DOI:10.1021/jacs.6b02343
