Technology Process of C72H78O10SSi
There total 4 articles about C72H78O10SSi which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
6-deoxy-6-C-(2'-ethanoic acid)-1,2,3,4,5-O-penta-O-benzyl-D-myo-inositol;
With
2,4,6-trichlorobenzoyl chloride; triethylamine;
In
tetrahydrofuran;
at 0 ℃;
for 3.5h;
4-O-tert-butyl(diphenyl)silyl-1,2-O-isopropylidene-D-erythro-S-phenyl monothiohemiacetal;
With
dmap;
In
tetrahydrofuran; toluene;
at 0 ℃;
for 1h;
DOI:10.1039/c3ob41337c
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ozone / methanol; dichloromethane / -78 °C
1.2: 2 h / -78 - 20 °C
2.1: sodium dihydrogenphosphate; sodium chlorite / water; tetrahydrofuran / 2 h / 20 °C
3.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 3.5 h / 0 °C
3.2: 1 h / 0 °C
With
sodium chlorite; sodium dihydrogenphosphate; 2,4,6-trichlorobenzoyl chloride; ozone; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water;
3.1: |Yamaguchi Lactonization / 3.2: |Yamaguchi Lactonization;
DOI:10.1039/c3ob41337c
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 °C / Inert atmosphere
1.2: 0.5 h / 0 - 20 °C
2.1: ozone / methanol; dichloromethane / -78 °C
2.2: 2 h / -78 - 20 °C
3.1: sodium dihydrogenphosphate; sodium chlorite / water; tetrahydrofuran / 2 h / 20 °C
4.1: 2,4,6-trichlorobenzoyl chloride; triethylamine / tetrahydrofuran / 3.5 h / 0 °C
4.2: 1 h / 0 °C
With
sodium chlorite; sodium dihydrogenphosphate; 2,4,6-trichlorobenzoyl chloride; tetra-(n-butyl)ammonium iodide; sodium hydride; ozone; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;
4.1: |Yamaguchi Lactonization / 4.2: |Yamaguchi Lactonization;
DOI:10.1039/c3ob41337c
