N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide

Base Information

• Chemical Name: N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide
• CAS No.: 371156-90-0
• Molecular Formula: C₂₅H₂₇NO₄S
• Molecular Weight: 437.56
• Mol file: 371156-90-0.mol

Synonyms:N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide

Chemical Property of N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide

There total 5 articles about N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfanyl)ethylformamide (371156-88-6) → N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide (371156-90-0)

Guidance literature:

With sodium periodate; In methanol; at 20 ℃; for 1.5h;

DOI:10.1248/cpb.49.979

Reference yield:

1-phenyl-2-(phenylthio)ethanone (16222-10-9) → N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide (371156-90-0)

Guidance literature:

Multi-step reaction with 4 steps

1: Ti(O-iPr)4 / 3 h / 80 °C

2: NaBH₄ / methanol / 1 h / 20 °C

3: 99 percent / formic acid / 1 h / 60 °C

4: 97 percent / aq. NaIO₄ / methanol / 1.5 h / 20 °C

With titanium(IV) isopropylate; sodium tetrahydroborate; sodium periodate; formic acid; In methanol;

DOI:10.1248/cpb.49.979

Reference yield:

2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) → N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfinyl)ethylformamide (371156-90-0)

Guidance literature:

Multi-step reaction with 4 steps

1: Ti(O-iPr)4 / 3 h / 80 °C

2: NaBH₄ / methanol / 1 h / 20 °C

3: 99 percent / formic acid / 1 h / 60 °C

4: 97 percent / aq. NaIO₄ / methanol / 1.5 h / 20 °C

With titanium(IV) isopropylate; sodium tetrahydroborate; sodium periodate; formic acid; In methanol;

DOI:10.1248/cpb.49.979

upstream raw materials:

N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfanyl)ethylformamide

1-phenyl-2-(phenylthio)ethanone

2-(3,4-dimethoxyphenyl)-ethylamine

N-2-(3,4-dimethoxyphenyl)ethyl-1-phenyl-(2-phenylsulfanyl)ethylamine

Downstream raw materials:

N-2-(3,4-dimethoxyphenyl)ethyl-N-[(E)-1-phenyl-2-(phenylsulfanyl)ethenyl]formamide

2-formyl-6,7-dimethoxy-1-phenyl-1-phenylsulfanylmethyl-1,2,3,4-tetrahydroisoquinoline

3-formyl-7,8-dimethoxy-2-phenyl-1,2,4,5-tetrahydro-3H-3-benzazepine

2-formyl-6,7-dimethoxy-1-methyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline