(R)-1'-benzyl-[1,3']bipyrrolidinyl

Base Information

Chemical Name:(R)-1'-benzyl-[1,3']bipyrrolidinyl
CAS No.:900164-96-7
Molecular Formula:C₁₅H₂₂N₂
Molecular Weight:230.353
Hs Code.:

Synonyms:(R)-1'-benzyl-[1,3']bipyrrolidinyl

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1'-benzyl-[1,3']bipyrrolidinyl

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Technology Process of (R)-1'-benzyl-[1,3']bipyrrolidinyl

There total 2 articles about (R)-1'-benzyl-[1,3']bipyrrolidinyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 110-52-1
1,4-dibromo-butane

: 114715-39-8
(R)-1-benzyl-3-aminopyrrolidine

: 900164-96-7
(R)-1'-benzyl-[1,3']bipyrrolidinyl

Guidance literature:: With potassium carbonate; In ethanol; at 60 ℃; for 24h;
DOI:10.1016/j.tetasy.2010.04.038

Reference yield:

: 696-59-3
cis,trans-2,5-dimethoxytetrahydrofuran

: 114715-39-8
(R)-1-benzyl-3-aminopyrrolidine

: 900164-96-7
(R)-1'-benzyl-[1,3']bipyrrolidinyl

Guidance literature:: cis,trans-2,5-dimethoxytetrahydrofuran; (R)-1-benzyl-3-aminopyrrolidine; With sodium tetrahydroborate; sulfuric acid; In tetrahydrofuran; water; at 10 - 20 ℃; for 288h;

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃; pH=< 10;

Reference yield: 100.0%

: 900164-96-7
(R)-1'-benzyl-[1,3']bipyrrolidinyl

: 913702-34-8,957540-36-2
(R)-1,3'-bipyrrolidine dihydrochloride

Guidance literature:: With hydrogenchloride; 10% palladium on carbon; hydrogen; In methanol; water; at 40 ℃; for 24h; under 30003 Torr;
DOI:10.1016/j.tetasy.2010.04.038