1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole

Base Information

• Chemical Name: 1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole
• CAS No.: 710982-46-0
• Molecular Formula: C₂₃H₁₉F₂NO
• Molecular Weight: 363.407
• Mol file: 710982-46-0.mol

Synonyms:1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole

Chemical Property of 1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole

There total 1 articles about 1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole (710982-40-4) + 4-Fluorobenzyl bromide (459-46-1) → 1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole (710982-46-0)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 0.25h;

Reference yield:

oxalyl dichloride (79-37-8) + 1-(4-fluoro-benzyl)-5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole (710982-46-0) → {1-(4-fluorobenzyl)-5-[2-(4-fluorophenyl)ethoxy]-1H-indol-3-yl}(oxo)acetic acid (710981-49-0)

Guidance literature:

In tetrahydrofuran; at 20 ℃;

upstream raw materials:

5-[2-(4-fluoro-phenyl)-ethoxy]-1H-indole

4-Fluorobenzyl bromide

Downstream raw materials:

{1-(4-fluorobenzyl)-5-[2-(4-fluorophenyl)ethoxy]-1H-indol-3-yl}(oxo)acetic acid