1-Bromo-4-(2-propoxyethoxy)benzene

Base Information

• Chemical Name: 1-Bromo-4-(2-propoxyethoxy)benzene
• CAS No.: 279262-26-9
• Molecular Formula: C₁₁H₁₅BrO₂
• Molecular Weight: 259.143
• DSSTox Substance ID: DTXSID801295410
• Mol file: 279262-26-9.mol

Synonyms:1-bromo-4-(2-propoxyethoxy)benzene;279262-26-9;SCHEMBL7254241;1-p-bromophenoxy-2-propoxyethane;DTXSID801295410;AKOS010796753;2-(4-Bromophenoxy)ethanol, n-propyl ether

Chemical Property of 1-Bromo-4-(2-propoxyethoxy)benzene

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 258.02554
• Heavy Atom Count: 14
• Complexity: 133

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCOCCOC1=CC=C(C=C1)Br

Technology Process of 1-Bromo-4-(2-propoxyethoxy)benzene

There total 3 articles about 1-Bromo-4-(2-propoxyethoxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-(4-bromophenoxy)ethanol (34743-88-9) + propyl bromide (106-94-5) → 1-bromo-4-(2-propoxyethoxy)benzene (279262-26-9)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In water; dimethyl sulfoxide; at 20 - 50 ℃;

Reference yield: 98.0%

→ 1-bromo-4-(2-propoxyethoxy)benzene (279262-26-9)

Guidance literature:

Reference yield: 78.0%

4-bromo-phenol (106-41-2) + 2-chloroethyl propyl ether (42149-74-6) → 1-bromo-4-(2-propoxyethoxy)benzene (279262-26-9)

Guidance literature:

With potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1248/cpb.52.577

upstream raw materials:

4-bromo-phenol

2-chloroethyl propyl ether

2-(4-bromophenoxy)ethanol

propyl bromide

Downstream raw materials:

{4-[2-(propoxy)ethoxy]phenyl}boronic acid