42149-74-6Relevant articles and documents
Preparation method of chloro-aliphatic ether
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Paragraph 0099; 0112; 0117-0118; 0124; 0129; 0130, (2017/10/13)
The invention discloses a preparation method of chloro-aliphatic ether, and aims to solve the problems that when 2-propoxy-dichloroethane is synthesized by adopting an existing method, a large amount of sulphur dioxide is produced and the amount of wastewater is large, solid waste pollution can be produced if a phase catalyst is recycled and applied mechanically, and when triphosgene is used as a chlorating agent, the price of the triphosgene is expensive so that the triphosgene is not suitable for large-scale industrial production. The method comprises the following steps: 1) carrying out reaction on a compound shown in a formula (I) and carbonyl chloride to prepare a compound shown in a formula (II); (2) carrying out decarboxylic reaction on the compound shown in the formula (II) to prepare a compound shown in a formula (III). According to the preparation method disclosed by the invention, a brand-new route for preparing the chloro-aliphatic ether is provided, so that the yield of the chloro-aliphatic ether is high, and the production cost can be effectively reduced; moreover, HC1, CO2 and a small amount of high-salinity wastewater only can be produced, so that three wastes are little, the environment protection is achieved, and the environment protection cost is low; in addition, the method also can be applied to preparation of multi-structure chloro-aliphatic ether, has a higher application value and wide application prospect, and is worthy of massively popularized and applied.
Production method of 2-propoxyethyl chloride
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Paragraph 0012; 0017-0032, (2017/08/30)
The invention relates to a production method of 2-propoxyethyl chloride and belongs to the technical field of fine chemical intermediate organic synthesis. The synthesis process comprises the following steps: preparing a crude product by taking ethylene glycol monopropyl ether and excessive sulfoxide chloride as main raw materials and adopting an efficient catalyst through heating and heat preservation, wherein the reaction rate is controlled by dropwise adding sulfoxide chloride; and performing neutralization, hydrolysis, and liquid separation after standingto obtain 2-propoxyethyl chloride. Compared with the existing process, the synthesis process has the advantages that the catalyst has higher catalytic efficiency and is cheap and easily available; the technological process is simple and convenient; the catalyst used in the existing process and hydrochloric acid in the crude product form a complex easily, so that the product has precipitates and the product yield is influenced; and the crude product prepared by the catalyst is clear and transparent, the product can be obtained without water washing, the quality is stable, the product content reaches above 99.5 percent, the yield is more than 99.0 percent, the production cost is lower, and the synthesis process is particularly suitable for industrialized production.
Preparation process of 2-propoxy chloroethane
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Paragraph 0016; 0017; 0018; 0019; 0020; 0021; 0022-0031, (2017/09/02)
The invention relates to a preparation process of 2-propoxy chloroethane and belongs to the technical field of organic synthesis of fine chemical intermediates. The synthetic process comprises the following steps: by taking ethylene glycol monopropyl ether and excess thionyl chloride as raw materials and adopting a high efficiency composite catalyst, controlling the reaction rate through dropwise adding the thionyl chloride, raising the temperature and preserving the temperature to obtain a crude product, neutralizing, hydrolyzing, standing and layering to obtain the 2-propoxy chloroethane. Compared with the prior art, the preparation process disclosed by the invention has the advantages that the catalyst is higher in catalytic efficiency, low in price and easy to get; the process is simple, safe and reliable; the product is high in yield and stable in quality; the product content is up to above 99.0%; the yield is greater than 98.5%; catalysts used in the prior art easily react with little hydrochloric acid contained in the product to form complex salt which is a precipitate in the 2-propoxy chloroethane and then the product quality is influenced; and the preparation process is particularly suitable for industrial production.
