3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine

Base Information

Chemical Name:3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine
CAS No.:208519-14-6
Molecular Formula:C₁₀H₁₁N₃S
Molecular Weight:205.283
Hs Code.:
DSSTox Substance ID:DTXSID401262659

Synonyms:208519-14-6;1H-Pyrazol-3-amine, 5-[4-(methylthio)phenyl]-;3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine;SCHEMBL6966609;DTXSID401262659;AKOS017766372;5-[4-(Methylthio)phenyl]-1H-pyrazol-3-amine;EN300-1150427;5-[4-(methylsulfanyl)phenyl]-1H-pyrazol-3-amine;3-(4-(Methylthio)phenyl)-1H-pyrazol-5-amine, AldrichCPR

Suppliers and Price of 3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:205.06736854
Heavy Atom Count:14
Complexity:180

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CSC1=CC=C(C=C1)C2=CC(=NN2)N

Technology Process of 3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine

There total 3 articles about 3-[4-(Methylsulfanyl)phenyl]-1H-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1344045-96-0
3-[4-(methylsulfanyl)phenyl]-3-oxopropanenitrile

: 208519-14-6
5-[4-(methylsulfanyl)phenyl]-1H-pyrazol-3-amine

Guidance literature:: With hydrogenchloride; hydrazine hydrate; In ethanol; water; for 2.5h; Reflux;
DOI:10.1016/j.bmc.2013.02.048

Reference yield:

: 42445-46-5
2-bromo-1-(4-methylsulfanyl-phenyl)-ethanone

: 208519-14-6
5-[4-(methylsulfanyl)phenyl]-1H-pyrazol-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: water; ethanol / 0 - 20 °C

2: hydrazine hydrate; hydrogenchloride / water; ethanol / 2.5 h / Reflux

With hydrogenchloride; hydrazine hydrate; In ethanol; water;
DOI:10.1016/j.bmc.2013.02.048

Reference yield:

: 1778-09-2
4-(Methylthio)acetophenone

: 208519-14-6
5-[4-(methylsulfanyl)phenyl]-1H-pyrazol-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; pyridinium perbromide hydrobromide; hydrogen bromide / 0 - 20 °C

2: water; ethanol / 0 - 20 °C

3: hydrazine hydrate; hydrogenchloride / water; ethanol / 2.5 h / Reflux

With hydrogenchloride; pyridinium perbromide hydrobromide; hydrogen bromide; hydrazine hydrate; acetic acid; In ethanol; water;
DOI:10.1016/j.bmc.2013.02.048