5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

Base Information

Chemical Name:5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide
CAS No.:1516902-78-5
Molecular Formula:C₂₀H₁₄BrNO₄
Molecular Weight:412.239
Hs Code.:

Synonyms:5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

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Technology Process of 5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

There total 1 articles about 5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 1353747-19-9
5-((4-bromobenzyl)oxy)-4-oxo-4H-chromene-2-carboxylic acid

: 2450-71-7
Propargylamine

: 1516902-78-5
5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1021/jm401649j

Reference yield: 46.0%

: 1516902-78-5
5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

: 622-79-7
benzyl azide

: 1516902-80-9
5-(4-bromobenzyloxy)-4-oxo-4H-chromene-2-carboxylic acid (1-benzyl-1H-[1,2,3]-triazol-4-ylmethyl)amide

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1021/jm401649j

Reference yield: 46.0%

: 1516902-78-5
5-(4-bromo-benzyloxy)-4-oxo-4H-chromene-2-carboxylic acid prop-2-ynylamide

: 107047-10-9
p-bromobenzylazide

: 1516902-81-0
5-(4-bromobenzyloxy)-4-oxo-4H-chromene-2-carboxylic acid [1-(4-bromobenzyl)-1H-[1,2,3]-triazol-4-ylmethyl]amide

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1021/jm401649j