Methyl 1-(4-chlorophenyl)pyrrole-2-carboxylate

Base Information

• Chemical Name: Methyl 1-(4-chlorophenyl)pyrrole-2-carboxylate
• CAS No.: 13179-30-1
• Molecular Formula: C₁₂H₁₀ClNO₂
• Molecular Weight: 235.67
• DSSTox Substance ID: DTXSID70372403
• Wikidata: Q82160094

Synonyms:methyl 1-(4-chlorophenyl)pyrrole-2-carboxylate;13179-30-1;methyl 1-(4-chlorophenyl)-1H-pyrrole-2-carboxylate;Maybridge1_007639;HMS563D05;DTXSID70372403

Chemical Property of Methyl 1-(4-chlorophenyl)pyrrole-2-carboxylate

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 235.0400063
• Heavy Atom Count: 16
• Complexity: 251

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC(=O)C1=CC=CN1C2=CC=C(C=C2)Cl

Technology Process of Methyl 1-(4-chlorophenyl)pyrrole-2-carboxylate

There total 3 articles about Methyl 1-(4-chlorophenyl)pyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

4-chloro-N-prop-2-ynylaniline (22774-67-0) + methyl 2-methoxy-2-(piperidin-1-yl)acetate (13887-54-2) → methyl 1-(4-chlorophenyl)-1H-pyrrole-2-carboxylate (13179-30-1)

Guidance literature:

With copper dichloride; In toluene; at 100 ℃; for 2h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1002/ejoc.201500098

Reference yield:

methyl Pyrrole-2-carboxylate (1193-62-0) + 4-Chlorophenylboronic acid (1679-18-1) → methyl 1-(4-chlorophenyl)-1H-pyrrole-2-carboxylate (13179-30-1)

Guidance literature:

With copper diacetate; In methanol; at 20 - 60 ℃;

DOI:10.1016/j.bmcl.2017.06.028

Reference yield:

→ methyl 1-(4-chlorophenyl)-1H-pyrrole-2-carboxylate (13179-30-1)

Guidance literature:

4c, Chromatogr. an Al2O3 in CCl4 od. Bzl.;

upstream raw materials:

4-chloro-N-prop-2-ynylaniline

methyl 2-methoxy-2-(piperidin-1-yl)acetate

methyl Pyrrole-2-carboxylate

4-Chlorophenylboronic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 13179-30-1 methyl 1-(4-chlorophenyl)-1H-pyrrole-2-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send