p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside

Base Information

• Chemical Name: p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside
• CAS No.: 359687-39-1
• Molecular Formula: C₂₆H₃₂N₂O₇
• Molecular Weight: 484.549

Synonyms:p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside

Chemical Property of p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside

There total 12 articles about p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(4-hydroxyphenyl)propionic acid benzyl ester (31770-76-0) → p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside (359687-39-1)

Guidance literature:

Multi-step reaction with 11 steps

1.1: 59 percent / SnCl₄ / CH₂Cl₂ / 1 h / -19 °C

2.1: 74 percent / NaOBn / phenylmethanol / 1 h / 0 °C / pH 11

3.1: (Bu₃Sn)2O / toluene / 2 h / Heating

3.2: 66 percent / toluene / 72 h / 20 °C

4.1: 145 mg / pyridine / 4 h / 20 °C

5.1: 92 percent / 18-crown-6 / benzene / 4 h / 20 °C

6.1: 96 percent / tetrabutylammonium azide / hexane / 20 °C / ultrasonication

7.1: H₂ / Pd/C / benzene / 1 h

8.1: 311 mg / 0.5 h / 20 °C

9.1: 91 percent / H₂ / Pd(OH)2 / ethanol / 1 h

10.1: 81 percent / WSC / CH₂Cl₂ / 1 h / 0 °C

11.1: 333 mg / NaOMe / methanol / 2 h / pH 10

With pyridine; 18-crown-6 ether; hydrogen; sodium methylate; tetrabutylammoniun azide; tin(IV) chloride; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; sodium phenyl-methanolate; bis(tri-n-butyltin)oxide; palladium dihydroxide; palladium on activated charcoal; In methanol; ethanol; hexane; dichloromethane; toluene; benzyl alcohol; benzene;

DOI:10.1081/CAR-100103953

Reference yield:

4-hydroxyphenylpropionic acid (501-97-3) → p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside (359687-39-1)

Guidance literature:

Multi-step reaction with 12 steps

1.1: 765 mg / KHCO₃ / dimethylformamide / 12 h / 20 °C

2.1: 59 percent / SnCl₄ / CH₂Cl₂ / 1 h / -19 °C

3.1: 74 percent / NaOBn / phenylmethanol / 1 h / 0 °C / pH 11

4.1: (Bu₃Sn)2O / toluene / 2 h / Heating

4.2: 66 percent / toluene / 72 h / 20 °C

5.1: 145 mg / pyridine / 4 h / 20 °C

6.1: 92 percent / 18-crown-6 / benzene / 4 h / 20 °C

7.1: 96 percent / tetrabutylammonium azide / hexane / 20 °C / ultrasonication

8.1: H₂ / Pd/C / benzene / 1 h

9.1: 311 mg / 0.5 h / 20 °C

10.1: 91 percent / H₂ / Pd(OH)2 / ethanol / 1 h

11.1: 81 percent / WSC / CH₂Cl₂ / 1 h / 0 °C

12.1: 333 mg / NaOMe / methanol / 2 h / pH 10

With pyridine; 18-crown-6 ether; hydrogen; sodium methylate; tetrabutylammoniun azide; tin(IV) chloride; potassium hydrogencarbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; sodium phenyl-methanolate; bis(tri-n-butyltin)oxide; palladium dihydroxide; palladium on activated charcoal; In methanol; ethanol; hexane; dichloromethane; N,N-dimethyl-formamide; toluene; benzyl alcohol; benzene;

DOI:10.1081/CAR-100103953

Reference yield:

p-[2-(benzyloxycarbonyl)ethyl]phenyl β-D-galactopyranoside (359686-45-6) → p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside (359687-39-1)

Guidance literature:

Multi-step reaction with 9 steps

1.1: (Bu₃Sn)2O / toluene / 2 h / Heating

1.2: 66 percent / toluene / 72 h / 20 °C

2.1: 145 mg / pyridine / 4 h / 20 °C

3.1: 92 percent / 18-crown-6 / benzene / 4 h / 20 °C

4.1: 96 percent / tetrabutylammonium azide / hexane / 20 °C / ultrasonication

5.1: H₂ / Pd/C / benzene / 1 h

6.1: 311 mg / 0.5 h / 20 °C

7.1: 91 percent / H₂ / Pd(OH)2 / ethanol / 1 h

8.1: 81 percent / WSC / CH₂Cl₂ / 1 h / 0 °C

9.1: 333 mg / NaOMe / methanol / 2 h / pH 10

With pyridine; 18-crown-6 ether; hydrogen; sodium methylate; tetrabutylammoniun azide; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; bis(tri-n-butyltin)oxide; palladium dihydroxide; palladium on activated charcoal; In methanol; ethanol; hexane; dichloromethane; toluene; benzene;

DOI:10.1081/CAR-100103953

upstream raw materials:

4-hydroxyphenylpropionic acid

3-(4-hydroxyphenyl)propionic acid benzyl ester

p-vinylbenzylamine

p-[2-(benzyloxycarbonyl)ethyl]phenyl β-D-galactopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 359687-39-1 p-[2-[N-(p-vinylbenzyl)carbamoyl]ethyl]phenyl 2-acetamido-2-deoxy-β-D-mannopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send