N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

Base Information

Chemical Name:N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine
CAS No.:169882-78-4
Molecular Formula:C₁₈H₂₂BrN₃O
Molecular Weight:376.296
Hs Code.:

Synonyms:N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

Suppliers and Price of N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

There total 6 articles about N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 169882-77-3
N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-carboxy-6-methylpyrimidinamine

: 169882-78-4
N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

Guidance literature:: With hydrogenchloride; methyllithium; In tetrahydrofuran;

Reference yield: 43.0%

: 917-54-4
methyllithium

: 169882-77-3
N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-carboxy-6-methylpyrimidinamine

: 169882-78-4
N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

: 2-{2-[(2-bromo-4-isopropyl-phenyl)-ethyl-amino]-6-methyl-pyrimidin-4-yl}-propan-2-ol

Guidance literature:: With cerium(III) chloride; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃;
DOI:10.1016/S0968-0896(99)00182-0

Reference yield:

: 51605-97-1
2-bromo-4-isopropylaniline

: 169882-78-4
N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine

Guidance literature:: Multi-step reaction with 4 steps

1: 1,4-dioxane / 20 h / Heating / reflux

2: sodium hydride / tetrahydrofuran / 24 h / Heating / reflux

3: sodium hydroxide / ethanol / 18 h / Heating / reflux

4: methyllithium; cerium chloride / tetrahydrofuran / 24 h / -78 - 20 °C

With sodium hydride; sodium hydroxide; methyllithium; cerium chloride; In tetrahydrofuran; 1,4-dioxane; ethanol;