(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

Base Information

Chemical Name:(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane
CAS No.:1046470-56-7
Molecular Formula:C₂₆H₃₇NO₂SSi
Molecular Weight:455.737
Hs Code.:

Synonyms:(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

Suppliers and Price of (1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

There total 1 articles about (1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1046470-60-3
(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-(formylmethyl)cyclopropane

: 343338-28-3
(S)-2-methylpropane-2-sulfinamide

: 1046470-56-7
(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

Guidance literature:: With copper(II) sulfate; In dichloromethane; at 20 ℃;
DOI:10.1021/ol8013304

Reference yield:

: 1046470-56-7
(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

: 1826-67-1
vinyl magnesium bromide

: C₂₈H₄₁NO₂SSi

: 1046470-59-0
C₂₈H₄₁NO₂SSi

Guidance literature:: In toluene; at 110 ℃; optical yield given as %de; stereoselective reaction;
DOI:10.1021/ol8013304

Reference yield:

: 1046470-56-7
(1S,2S)-2-[(tert-butyldiphenylsiloxy)methyl]-1-[2-((S)-tert-butylsulfinyl)iminoethyl]cyclopropane

: C₂₈H₂₆N₄O₃

Guidance literature:: Multi-step reaction with 7 steps

1: tetrahydrofuran; toluene / 0.17 h / Reflux

2: hydrogenchloride / tetrahydrofuran; water / 0.17 h / 0 °C

3: sodium carbonate / tetrahydrofuran; water / 36 h / 20 °C

4: hydrogenchloride / ethyl acetate; water; methanol / 2 h / 20 °C

5: Dess-Martin periodane / dichloromethane / 2 h / 20 °C

6: sodium chlorite; sodium dihydrogen phosphate dihydrate; 2-methyl-but-2-ene / tetrahydrofuran; water; tert-butyl alcohol / 5 h / 20 °C

7: triethylamine; diphenyl phosphoryl azide / dichloromethane / 15.33 h / 0 - 20 °C

With hydrogenchloride; sodium chlorite; 2-methyl-but-2-ene; sodium dihydrogen phosphate dihydrate; diphenyl phosphoryl azide; sodium carbonate; Dess-Martin periodane; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate; toluene; tert-butyl alcohol;
DOI:10.1021/jm4002296