3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose

Base Information

• Chemical Name: 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose
• CAS No.: 352020-72-5
• Molecular Formula: C₃₅H₃₈O₆
• Molecular Weight: 554.683
• Mol file: 352020-72-5.mol

Synonyms:3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose

Chemical Property of 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose

There total 2 articles about 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methylmagnesium chloride (676-58-4) + 2,3,4,6-tetra-O-benzyl-D-galactonolactone (82598-84-3) → 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose (352020-72-5)

Guidance literature:

In tetrahydrofuran; at -78 - -20 ℃; for 2h;

DOI:10.1021/jo0255227

Reference yield: 82.5%

methyllithium (917-54-4) + 2,3,4,6-tetra-O-benzyl-D-galactonolactone (82598-84-3) → 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose (352020-72-5)

Guidance literature:

In tetrahydrofuran; diethyl ether; at -78 ℃; for 1h;

DOI:10.1016/S0040-4020(01)00321-0

Reference yield: 89.1%

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) + 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranose (352020-72-5) → methyl O-(2',3',4',6'-tetra-O-benzyl-1'-C-methyl-α-D-galactopyranosyl)-(1'->6)-2,3,4-tri-O-benzyl-α-D-glucoside (352020-81-6)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1016/S0040-4020(01)00321-0

upstream raw materials:

methyllithium

2,3,4,6-tetra-O-benzyl-D-galactonolactone

methylmagnesium chloride

Downstream raw materials:

methyl O-(2',3',4',6'-tetra-O-benzyl-1'-C-methyl-α-D-galactopyranosyl)-(1'->6)-2,3,4-tri-O-benzyl-α-D-glucoside

(3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]tetrahydro-2H-pyran-2-one

3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranosyl-(2→1)-2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-galacto-hept-2-ulopyranosyl-(2→1)-2,3,4,6-tetra-O-acetyl-α-D-glucopyranoside