6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Base Information

Chemical Name:6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate
CAS No.:1263383-05-6
Molecular Formula:C₅₃H₉₀N₄O₂₀
Molecular Weight:1103.31
Hs Code.:

6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Synonyms:6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Suppliers and Price of 6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

There total 8 articles about 6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1263383-04-5
6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl alcohol

: 920-46-7,26937-45-1
Methacryloyl chloride

: 1263383-05-6
6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at -5 - 25 ℃;
DOI:10.1007/s11426-010-4136-3

Reference yield:

: (3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)phenyl)formic acid

: 1263383-05-6
6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Guidance literature:: Multi-step reaction with 5 steps

1: dicyclohexyl-carbodiimide / dichloromethane / 12 h / -15 - 25 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / -15 - 25 °C

3: hydrogenchloride / tetrahydrofuran; water / 10 h / 0 °C

4: N-ethyl-N,N-diisopropylamine / dichloromethane / -15 - 25 °C

5: dmap; triethylamine / dichloromethane / -5 - 25 °C

With hydrogenchloride; dmap; triethylamine; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1007/s11426-010-4136-3

Reference yield:

: 1263383-01-2
6-(tert-butoxycarbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl alcohol

: 1263383-05-6
6-((2S,4S)-1-(tert-butoxycarbonyl)-4-(tert-butoxycarbonylamino)pyrrolidine-2-carbonylamino)-2-(3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzamido)hexyl methacrylate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / tetrahydrofuran; water / 10 h / 0 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / -15 - 25 °C

3: dmap; triethylamine / dichloromethane / -5 - 25 °C

With hydrogenchloride; dmap; triethylamine; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1007/s11426-010-4136-3