1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine

Base Information

Chemical Name:1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine
CAS No.:1201663-79-7
Molecular Formula:C₂₀H₁₇ClFN
Molecular Weight:325.813
Hs Code.:

Synonyms:1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine

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Chemical Property of 1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine

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Technology Process of 1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine

There total 2 articles about 1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1172338-38-3
(4'-chlorobiphenyl-3-yl)methanamine hydrochloride

: 459-57-4
4-fluorobenzaldehyde

: 1201663-79-7
1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine

Guidance literature:: (4'-chlorobiphenyl-3-yl)methanamine hydrochloride; 4-fluorobenzaldehyde; In dichloromethane; isopropyl alcohol; at 20 ℃; for 1h;

With sodium tris(acetoxy)borohydride; In dichloromethane; isopropyl alcohol; at 20 ℃; for 3h; Inert atmosphere;

With sodium hydrogencarbonate; In dichloromethane; water; isopropyl alcohol; for 0.166667h;

Reference yield: 59.0%

: 140-75-0
para-fluorobenzylamine

: 139502-80-0
4'-chloro-[1,1'-biphenyl]-3-carbaldehyde

: 1201663-79-7
1-(4'-chlorobiphenyl-3-yl)-N-(4-fluorobenzyl)methanamine

Guidance literature:: para-fluorobenzylamine; 4'-chloro-[1,1'-biphenyl]-3-carbaldehyde; With acetic acid; In 1,2-dichloro-ethane; at 20 ℃; for 13.5h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; for 4h;

para-fluorobenzylamine;