2-Methoxydibenzothiophene

Base Information

Chemical Name:2-Methoxydibenzothiophene
CAS No.:22439-64-1
Molecular Formula:C₁₃H₁₀OS
Molecular Weight:214.288
Hs Code.:
DSSTox Substance ID:DTXSID001312056

Synonyms:2-methoxydibenzothiophene;SCHEMBL8964851;HBMHIQYZHOTGGE-UHFFFAOYSA-N;DTXSID001312056;22439-64-1

Suppliers and Price of 2-Methoxydibenzothiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Methoxydibenzothiophene

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:214.04523611
Heavy Atom Count:15
Complexity:231

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)SC3=CC=CC=C32

Technology Process of 2-Methoxydibenzothiophene

There total 4 articles about 2-Methoxydibenzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 15861-50-4
(2-bromophenyl)(4-methoxyphenyl)thioether

: 22439-64-1
2-methoxydibenzo[b,d]thiophene

: 5633-57-8
1-methoxy-4-(phenylsulfanyl)benzene

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium pivalate; In N,N-dimethyl acetamide; at 140 ℃; for 12h; Reagent/catalyst;
DOI:10.1021/ol4036209

Reference yield:

: 6320-02-1
o-bromothiophenol

: 22439-64-1
2-methoxydibenzo[b,d]thiophene

: 5633-57-8
1-methoxy-4-(phenylsulfanyl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuryl dichloride; triethylamine / dichloromethane / 0 - 20 °C

1.2: 1 h / 0 - 20 °C

2.1: palladium diacetate; trifluoroacetic acid / 0.75 h / 20 °C

3.1: potassium pivalate; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl acetamide / 12 h / 140 °C

With bis-triphenylphosphine-palladium(II) chloride; sulfuryl dichloride; palladium diacetate; potassium pivalate; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/ol4036209

Reference yield:

: 1541160-62-6
1-((2-bromo)-phenylthio)pyrrolidine-2,5-dione

: 100-66-3
methoxybenzene

: 22439-64-1
2-methoxydibenzo[b,d]thiophene

: 5633-57-8
1-methoxy-4-(phenylsulfanyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; trifluoroacetic acid / 0.75 h / 20 °C

2: potassium pivalate; bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl acetamide / 12 h / 140 °C

With bis-triphenylphosphine-palladium(II) chloride; palladium diacetate; potassium pivalate; trifluoroacetic acid; In N,N-dimethyl acetamide;
DOI:10.1021/ol4036209