(2-bromophenyl)(4-methoxyphenyl)thioether

Base Information

• Chemical Name: (2-bromophenyl)(4-methoxyphenyl)thioether
• CAS No.: 15861-50-4
• Molecular Formula: C₁₃H₁₁BrOS
• Molecular Weight: 295.2
• Mol file: 15861-50-4.mol

Synonyms:(2-bromophenyl)(4-methoxyphenyl)thioether

Chemical Property of (2-bromophenyl)(4-methoxyphenyl)thioether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2-bromophenyl)(4-methoxyphenyl)thioether

There total 10 articles about (2-bromophenyl)(4-methoxyphenyl)thioether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

para-iodoanisole (696-62-8) + o-bromothiophenol (6320-02-1) → (2-bromophenyl)(4-methoxyphenyl)thioether (15861-50-4)

Guidance literature:

With 1,1'-binaphthalene-2,2'-diamine; copper(II) bis(trifluoromethanesulfonate); caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 8h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.01.022

Reference yield: 94.0%

4-Methoxybenzenethiol (696-63-9) + 1-Bromo-2-iodobenzene (583-55-1) → (2-bromophenyl)(4-methoxyphenyl)thioether (15861-50-4)

Guidance literature:

With trans-9,10-dihydro-9,10-ethanoanthracene-11,12-dimethanol; caesium carbonate; copper(I) bromide; In acetonitrile; at 82 ℃; for 17h; Inert atmosphere; Sealed tube;

DOI:10.1055/s-0029-1217056

Reference yield: 92.0%

1-((2-bromo)-phenylthio)pyrrolidine-2,5-dione (1541160-62-6) + methoxybenzene (100-66-3) → (2-bromophenyl)(4-methoxyphenyl)thioether (15861-50-4)

Guidance literature:

With palladium diacetate; trifluoroacetic acid; at 20 ℃; for 0.75h;

DOI:10.1021/ol4036209

upstream raw materials:

para-iodoanisole

o-bromothiophenol

4-Methoxybenzenethiol

1-Bromo-2-iodobenzene

Downstream raw materials:

(2-iodophenyl)(4-methoxyphenyl)thioether

2-methoxydibenzo[b,d]thiophene

1-methoxy-4-(phenylsulfanyl)benzene

trans-[PdBr(C₆H₄(SC₆H₄OMe-4)-2)(PPh₃)2]

Refernces

• 1、 Chen, Bin,Lei, Tao,Li, Xu-Bing,Nan, Xiao-Lei,Tung, Chen-Ho,Wang, Jing-Hao,Wu, Hao-Lin,Wu, Li-Zhu. "Thiol Activation toward Selective Thiolation of Aromatic C-H Bond". supporting information. p. 3804 - 3809. Retrieved 2020/06/04.
• 2、 Kibriya, Golam,Mondal, Susmita,Hajra, Alakananda. "Visible-Light-Mediated Synthesis of Unsymmetrical Diaryl Sulfides via Oxidative Coupling of Arylhydrazine with Thiol". supporting information. p. 7740 - 7743. Retrieved 2018/12/14.