Technology Process of 4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyamine
There total 4 articles about 4-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]benzyloxyamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
In
tetrahydrofuran; ethanol;
for 3h;
Heating;
DOI:10.1248/cpb.51.138
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 93 percent / K2CO3 / dimethylformamide / 20 h / 20 °C
2: 90 percent / hydrazine monohydrate / ethanol; tetrahydrofuran / 3 h / Heating
With
potassium carbonate; hydrazine hydrate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.51.138
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium borohydrid / methanol (150 ml)-tetrahydrofurane; water
2: thionyl chloride / (2S)-N-methyl-1-phenylpropan-2-amine hydrate; toluene
3: potassium carbonate / water; N,N-dimethyl-formamide
4: sodium chloride; potassium carbonate; hydrazine hydrate / ethanol (40 ml)-tetrahydrofuran
With
thionyl chloride; sodium borohydrid; sodium chloride; potassium carbonate; hydrazine hydrate;
In
(2S)-N-methyl-1-phenylpropan-2-amine hydrate; ethanol (40 ml)-tetrahydrofuran; methanol (150 ml)-tetrahydrofurane; water; N,N-dimethyl-formamide; toluene;